About Us
Rappta Therapeutics is a lead-optimization stage biopharmaceutical company
We are working on a first-in-class series of anti-cancer molecules that reactivate a key tumor suppressor, protein phosphatase 2A (PP2A). Rappta’s proprietary tools and understanding of the target allow us to therapeutically reactivate PP2A, a critical enzyme regulating protein de-phosphorylation and tumor growth. As a result of PP2A’s central role in the regulation of protein phosphorylation, Rappta’s PP2A-reactivating technologies have platform potential in human therapeutic use.
What is PP2A
PP2A has a central role in human biology
The hyperphosphorylation of proteins because of the activation of kinases and inactivation of phosphatases is a hallmark of many diseases ranging from neurodegeneration to cancer.
Our Technology
Our proprietary approach to activate PP2A
PP2A is a key tumor suppressor and a critical enzyme regulating protein de-phosphorylation and tumor growth, but it has to date been very difficult to target pharmaceutically.
Our team
An experienced team of biopharmaceutical leaders
We have assembled a strong scientific, medchem, management, and commercial team based in Finland and the US. Our scientific team has published seminal papers on the structural, functional, and biological mechanisms of PP2A inactivation in human cancer.
News & Articles
Rappta Therapeutics Raises Series A Financing for the Development of Phosphatase 2A drugs
Unique phosphatase technology platform offers a new paradigm in oncology. EUR 9M financing, co-led by NVF and Novo Seeds with participation from Advent Life Sciences and a family office, to advance lead compounds to clinical candidate stage.
